YU Xiaodan (Ph.D.)

School of Public Health, Health Science Center, Xi’an Jiaotong University, Assistant Professor

Research areas:

Application of Fluorescent and Isotopic Imaging Probes Based on Organic Synthesis Strategies in Clinical Diagnostics

Organic Chemistry, Photocatalysis

Antimicrobial Peptides and Their Mechanisms of Action

Education:

2025/10-Present, School of Public Health, Xi’an Jiaotong University, Assistant Professor

2021/10-2024/03, Ecole doctoral 2MIB, Institut de Chimie Moléculaire et des Matériaux d'Orsay University of Paris Saclay（France），Organic Chemistry，Ph.D.

2018/09-2021/07, College of Chemistry and Materials Science, Fujian Normal University，Master

2014/09-2018/07, College of Chemistry and Chemical Engineering, Shaanxi Xueqian NormalUniversity，Bachelor

Published papers:

1. X. Yu, A. Desvals, Z. Chang, V, Oreve, D. J. Aitken, T. Boddaert. Light-initiated four-step domino-multicomponent synthesis of functionalized alkylidenecyclobutanes. Org. Lett. 2024, 26, 9915-9919. 

2. X. Yu, T. Boddaert, D. J. Aitken. Functionalized Alkylidenecyclobutanes from a Cyclopent-2-enone Substrate via a Tandem Photochemical Transformation and an Allylic Substitution Protocol. Adv. Synth.Catal. 2023, 365, 4002- 4007. 

3. X. Yu, L. Li, et al. A Cyclic Dipeptide from Marine Fungus Penicillium Chrysogenum DXY-1 Exhibits Anti-Quorum Sensing Activity. ACS Omega, 2021, 6, 7693 -7700.

4. L. Li, J. Li, X. Yu, et al. Antimicrobial peptides fight against Pseudomonas aeruginosa at a sub-inhibitory concentration via anti-QS pathway. Bioorg.chem., 2023, 141, 106922. 

5. A. Chang, Q. He, L. Li, X. Yu, S. Sun, H. Zhu. Exploring the quorum sensing inhibition of isolated chrysin from Penicillium chrysogenum DXY-1. Bioor.chem., 2021, 111, 104894.

Patents:

1. H. Zhu, A. Chang ,Y. Wang , W. Chen, Q. He, X. Yu, X. Dai. Production method of p-hydroxyphenylethyl alcohol and application of Penicillium chrysogenum [P]. CN110195084 B. 2022-10-28.

2. H. Zhu, Y. Wang , A. Chang , L. Li , X. Yu , Q. He .The Application of Tyrosine-Proline in the Preparation of Quorum Sensing Inhibitor [P]. CN201910684718. X. 2019-07-26.

Academic activities:

SECO 61st (Semaine d’etude en chimie Organique/Organic chemistry research work)        

05/2024

Oral presentation: Strategies for Synthesis and Functionalization of Alkylidenecyclobutanes

RCO 2024 (Rencontres de Chimie Organique/ Organic chemistry meetings)                  

04/2024

Poster: Photochemical cascade synthesis of functionalised alkylidenecyclobutanes.

2MIB doctoral school day 2023 program (JED)                                          

06/2023

Oral presentation: Photocascade for the Synthesis of Functionalized Alkylidenecyclobutanes.

Journees de Chimie Organique (JCO)                                                 

11/2022

Poster: Synthesis of Functionalized Alkylidenecyclobutanes.

Contact information:

Email: Xiaodan.yu@xjtu.edu.cn

Address: Building 21, Hongren Building, Xi’an Jiaotong University (Innovation Harbor Campus), Qindu District, Xianyang, Shaanxi Province, China,  710061