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中澳传染病联合研究中心

中澳传染病联合研究中心于2018年成立,由西安交通大学医学部与澳大利亚蒙纳士大学医学、护理与健康科学学院共同签署谅解备忘录正式建立。2019年9月,研究中心在西安交通大学中国西部科技创新港揭牌成立,由张磊教授担任首任主任。

自成立以来,中心发展迅速,从最初的4名成员,已成长为拥有80余名成员的跨学科研究团队。目前,中心拥有1名教授、2名副教授、4名博士后研究员、12名博士研究生和42名硕士研究生,并汇聚了来自中澳两校的多层次科研人才。短短数年间,研究中心已成为培养高水平公共卫生与传染病研究人才的重要基地。

研究中心的核心方向聚焦于人工智能、卫生经济学评价与流行病学建模,致力于将这些方法学与重大传染病和慢性病的防控实践紧密结合。中心利用理论流行病学、数学建模、大数据与人工智能技术,开展疾病监测预警、干预效果评估及政策模拟研究,为公共卫生决策提供科学依据。

近年来,研究中心积极拓展国内外合作网络,与多家知名科研机构和医疗机构建立长期伙伴关系,推动高水平学术交流与科研成果转化。中心科研成果丰硕,已在国际权威SCI期刊发表论文200余篇,并获得国家自然科学基金、国家级人才计划及国际合作等多渠道资助,累计经费超过1110万元人民币

通过方法学创新与实际应用的结合,研究中心不仅成为西部地区传染病防控与公共卫生研究的重要平台,也成为深化中澳高水平科研合作的重要桥梁。

中心主任:张磊 教授 029-82655135

教师个人主页:https://gr.xjtu.edu.cn/web/lei.zhang1/home


代表作 (n=27)

1. Zhang L, Chow EPF, Jing J, Zhuang X, Li X, He M, Sun H, Li X, Gorgens M, Wilson D, Wang L, Guo W, Li D, Cui Y, Wang L, Wang N,  Wu Z, Wilson DP. HIV prevalence in China: integration of surveillance data and a systematic review. Lancet Infectious Diseases 2013; 13(11):   955-63. (First author)

2.Su  S, Wong WCW, Zou Z, Cheng DD, Ong JJ, Chan P, Ji F, Yuen M-F, Zhuang G,  Seto W-K, Zhang L. Cost-effectiveness of universal screening for chronic hepatitis B virus infection in China: an economic evaluation. Lancet  Global Health. 2022;10(2):e278-e287.  (Senior author, corresponding author)

3.Zou Z, Fairley CK, Ong JJ, Hocking J, Canfell K, Ma  X, Chow EPF, Xu X, Zhang L*, Zhuang G*. Domestic HPV vaccine price and economic returns for cervical cancer prevention in China: a cost-effectiveness analysis. Lancet Global Health 2020; 8(10): e1335-e44.(Co-corresponding author)

4. Zhao R, Fairley CK, Cook AR, Phanuphak N, He S, Tieosapjaroen W, Chow EPF, Phillips TR, Jin Tan RK, Wei Y, Shen M, Zhuang G*, Ong JJ*, Zhang L*. Optimising HIV pre-exposure prophylaxis and testing strategies in men who have sex with men in Australia, Thailand, and China: a modelling study and cost-effectiveness analysis. Lancet Global Health 2024; 12(2): e243-e56. (Senior author, corresponding author)

5.Zhang L, Phanuphak N, Henderson K, Nonenoy S, Srikaew S, Shattock AJ, Kerr CC, Omune B, van Griensven F, Osornprasop S, Oelrichs R, Ananworanich J, Wilson DP. Scaling up of HIV treatment for men who have sex with men in  Bangkok: a modelling and costing study. Lancet  HIV 2015; 2(5): e200-e7. (First author)

6. Dong W, Liu Y, Bai R, Zhang L, Zhou M. The prevalence and associated disability burden of mental disorders in children and adolescents in China: a systematic analysis of data from the Global Burden of Disease Study. Lancet Reg Health West Pac 2025; 55: 101486. (co-corresponding author)

7.Xu  T, Dong W, Liu J, Yin P, Wang Z, Zhang L, Zhou M. Disease burden of  Parkinson's disease in China and its provinces from 1990 to 2021: findings  from the global burden of disease study 2021. Lancet Regional Health – Western Pacific 2024; 46: 101078. (Co-corresponding      author)

8.Liu  J, Liu M, Chai Z, Li C, Wang Y, Shen M, Zhuang G, Zhang L. Projected  rapid growth in diabetes disease burden and economic burden in China: a  spatio-temporal study from 2020 to 2030. Lancet Regional Health – Western Pacific 2023; 33. (Senior author, corresponding      author)

9.Zhang L,  Liu H, Zou Z, Su S, Ong JJ, Ji F, Cui F, Chan P-l, Ning Q, Li R, Shen M,      Fairley CK, Liu L, Seto W-K, Wong WCW. Shared-care  models are highly effective and cost-effective for managing chronic  hepatitis B in China: reinterpreting the primary care and specialty divide.  Lancet Regional Health - Western Pacific 2023:  100737. (First author)

10. Shen M, Zou Z, Bao H, Fairley CK, Canfell K, Ong JJ, Hocking J, Chow EPF, Zhuang G, Wang L, Zhang L. Cost-effectiveness of artificial intelligence-assisted liquid-based cytology testing for cervical cancer screening in China. Lancet Regional Health - Western Pacific 2023: 100726. (Senior author, corresponding author)

11. Zhang S, Wang C, Liu B, Lu Q-B, Shang J, Zhou Y, Jia J, Xu X, Rao H, Han B, Zhao T, Chen L, Xie M, Cui J, Du J, zeng J, huang N, Liu Y, Zhang L*, Zhuang H*, Cui F*. Cost-effectiveness of expanded antiviral treatment for chronic hepatitis B virus infection in China: an economic evaluation. Lancet Regional Health - Western Pacific 2023; 35: 100738. (Co-senior author, co-corresponding author)

12. Wang Y, Liu C, Hu W, Luo L, Shi D, Zhang J, Yin Q, Zhang L, Han X, He M. Economic evaluation for medical artificial intelligence: accuracy vs. cost-effectiveness in a diabetic retinopathy screening case. NPJ Digit Med 2024; 7(1): 43. (Co-senior author, co-corresponding author)

13. Hu W, Joseph S, Li R, Woods E, Sun J, Shen M, Jan CL, Zhu Z*, He M*, Zhang L*. Population impact and cost-effectiveness of artificial intelligence-based diabetic retinopathy screening in people living with diabetes in Australia: a cost effectiveness analysis. EClinicalMedicine 2024; 67. (Senior author, co-corresponding author)

14. Zou Z, Fairley CK, Ong JJ, Shen M, Chow EPF, Liu H, Xia R, Li R, Hocking J, Zhuang G, Zhang L. Impact of achieving WHO's 90-70-90 targets on cervical cancer elimination and potential benefits in preventing other HPV-related cancers in China: a modelling study. EClinicalMedicine 2024; 77: 102878. (Senior author, co-corresponding author)

15. Ong JJ, Ruan L, Lim AG, Bradshaw CS, Taylor-Robinson D, Unemo M, Horner PJ, Vickerman P, Zhang L. Impact of screening on the prevalence and incidence of Mycoplasma genitalium and its macrolide resistance in men who have sex with men living in Australia: A mathematical model. EClinicalMedicine 2021; 33: 100779. (Senior author, corresponding author)

16. Wulandari LPL, He SY, Fairley CK, Bavinton BR, Marie-Schmidt H, Wiseman V, Guy R, Tang W, Zhang L*, Ong JJ*. Preferences for pre-exposure prophylaxis for HIV: A systematic review of discrete choice experiments. EClinicalMedicine 2022; 51: 101507. (Co-senior author, co-corresponding author)

17. Kiggundu R, Soh QR, Tieosapjaroen W, Fairley CK, Tucker JD, Tang W, Zhang L, Ong JJ. Restarting pre-exposure prophylaxis (PrEP) for HIV: a systematic review and meta-analysis. EClinicalMedicine 2024; 72. (co-corresponding author)

18.Shang X, Peng W, Hill E, Szoeke C, He M, Zhang L.  Incidence of Medication-Treated Depression and  Anxiety Associated with Long-Term Cancer, Cardiovascular Disease,  Diabetes and Osteoarthritis in Community-dwelling Women and Men. EClinicalMedicine  2019; 15: 23-32. (Senior author, corresponding author)

19. Shen M, He S, Yao N, Li R, Wang J, Zhong W, Wang J, Wang H, Xie L, Zhuang G, Zhang L, Chen T. Real-world clinical data-driven modelling on the initiation time of antiviral prophylaxis among pregnant women with chronic hepatitis B infection. J Hepatol 2024. (co-corresponding author)

20. Li R, Shen M, Yang Q, Fairley CK, Chai Z-L, McIntyre R, Ong JJ, Liu H, Lu P, Hu W, Zou Z, Li Z, He S, Zhuang G, Zhang L. Global Diabetes Prevalence in COVID-19 Patients and Contribution to COVID-19– Related Severity and Mortality: A Systematic Review and Meta-analysis. Diabetes Care 2023: dc221943. (Senior author, corresponding author)

21. Liu J, Bai R, Chai Z, Cooper ME, Zimmet PZ, Zhang L. Low- and middle-income countries demonstrate rapid growth of type 2 diabetes: an analysis based on Global Burden of Disease 1990-2019 data. Diabetologia 2022. (Senior author, corresponding author)

22. Bao Y, Medland NA, Fairley CK, Wu J, Shang X, Chow EPF, Xu X, Ge Z, Zhuang X, Zhang L. Predicting the diagnosis of HIV and sexually transmitted infections among men who have sex with men using machine learning approaches. Journal of Infection 2021; 82(1): 48-59. (Senior author, corresponding author)

23. Soe NN, Latt PM, Yu Z, Lee D, Kim C-M, Tran D, Ong JJ, Ge Z, Fairley CK, Zhang L. Clinical features-based machine learning models to separate sexually transmitted infections from other skin diagnoses. Journal of Infection 2024: 106128. (Senior author, corresponding author)

24.Tao Y, Chen MY, Tucker JD, Ong JJ, Tang W, Wong NS, Chu M, Zhuang X,  Fairley CK, Zhang L. A Nationwide Spatiotemporal Analysis of      Syphilis over 21 Years and Implications for Prevention and Control in      China. Clinical  Infectious Diseases 2020; 70(1): 136-9. (Senior author, corresponding author)

25. Soe NN, Yu Z, Latt PM, Lee D, Ong JJ, Ge Z, Fairley CK, Zhang L. Evaluation of artificial intelligence-powered screening for sexually transmitted infections-related skin lesions using clinical images and metadata. BMC Medicine 2024; 22(1): 296. (Senior author, corresponding author)

26. Bao Y, Lu P, Wang M, Zhang X, Song A, Gu X, Ma T, Su S, Wang L, Shang X, Zhu Z, Zhai Y, He M, Li Z, Liu H, Fairley CK, Yang J, Zhang L. Exploring multimorbidity profiles in middle-aged inpatients: a network-based comparative study of China and the United Kingdom. BMC Medicine 2023; 21(1): 495. (Senior author, corresponding author)

27. Xu X, Chow EPF, Ong JJ, Hoebe C, Zou Z, Hocking JS, Fairley CK, Zhang L. Chlamydia trachomatis transmission between the oropharynx, urethra and anorectum in men who have sex with men: a mathematical model. BMC Medicine 2020; 18(1): 326. (Senior author, corresponding author)






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